Case Study 3:
Last Stage Breast Cancer

Name: Mrs. XXX
Country: Anyang, China
Age: 36

Oct 2006 Admitted to Henan XXX Tumour Hospital.
Diagnosed with
cancer of left breast.
Underwent modified radical mastectomy.
Dec 2006 underwent TA chemotherapy 4 cycles .
April 2007 discovered tumour above left clavicle.
Needle biopsy revealed
metastasis in mammary gland lymph
nodes.
Also discovered metastasis in both lungs and mediastinum.
Underwent Chemo again but was not found to be effective.
Disease continued to worsen with emergence of pleural effusion.
The doctors advised her to seek treatment elsewhere.
June 2007 she arrived at the hospital for treatment.

Pathological diagnosis on admission to You Hao hospital:
Poorly differentiated adenocarcinoma of the left breast,
Partly clear cell carcinoma, partly medullary carcinoma,
Vascular invasion.
Immunohistochemical staining test results:
ER(+),  PR(+), CERBB-2 (+++), CA15-3 (++) with
Metastases in both lungs, mediastinum, upper left clavicular
lymph nodes,
And Fluid retention in the thoracic cavity.

Treatment:
Due to the fact that the disease was in a very advanced stage
and chemotherapy was no longer a viable option, the specialists
proposed the use of biotherapy.
After one course of conventional biotherapy treatment (cord
blood CIK) the patient reported less chest pain, less chest
distress, and the clavicular mass showed significant reduction in
size.
However after half a month the supraclavicular lymph node
tumours showed enlargement.
The second round of biotherapy did not result in much obvious
improvement.
The patient displayed symptoms of taking a turn for the worse.
There was increased pleural effusion,
chest pain,  unable to lie flat on her back during sleep, required
pleural effusion drainage every 2-3 days.
Increased  metastatic  foci in the lungs, infringement on the
bronchial tubes.
Severe coughing day and night, unable to sleep at night.
Poor appetite, weak,  did not even have the strength to get out
of bed.

23 July 2007 PET/CT scan showed:
1) Recurrence and metastasis of cancer after modified
radical mastectomy of left breast and chemotherapy.  
Had nuclear implantation done.
Wide recurrence of cancer in the left chest wall.
2) Diffuse metastasis in both lungs, and both sides of the
thymus with medium quantity of dropsy.
3) Multiple metastasis in lymph nodes above both
clavicles,  beneath left armpit,  in bilateral porta pulmonis,
and mediastinum.
4) Systemic multiple metastases in bones.

Clinical symptoms and examinations indicated that the disease
was at a very advanced stage.
The doctors felt that at any time there was mortal danger to the
patient. They did not have any options except  to advise the
patient to return home to Anyang as soon as possible.

Miraculous turnaround
From Guangzhou to Anyang by train is a 20 odd hour journey. For
the safety of the patient, the doctors planned to drain out the
fluid from the chest before discharge from the hospital and
considered to do biotherapy one more time to improve the
condition of the patient for her safe return to her hometown.
Upon admission to the hospital it was discovered upon
examination that the patient’s immunocyte count was  1195/µl
and that of her husband’s was 3242/µl which was almost 3 times
as much. The doctors decided to try out a new method of
preparing the biotherapy medicine – that of using the
husband’s immunocytes for the  preparation of  the CIK
treatment for the patient. Till then this method was yet
unreported anywhere  within China and abroad. It was a bold
attempt and resulted in a miracle.
26 July 2007 For the first time for the patient and very possibly
in the medical history  of China, healthy adult blood was used in
the preparation of CIK and was administered.
27 July 2007 morning 8am during ward visit: The patient
showed marked improvement in alertness and energy levels,
reported less coughing during the night – only 3 times and had
improved sleep during the night before.
29 July 2007 conclusion of biotherapy treatment. The response
of the patient was extremely positive. The coughing had almost
disappeared.  Patient was able to sleep well. Appetite
singnificantly improved. First time in a month that patient was
able to get out of bed to tidy the room and to cook a meal. The
medical doctor in charge remarked that of all the cases receiving
CIK biotherapy treatment that this was the best they had seen.
Under the positive influence of the biotherapy treatment the
patient arrived home in Anyang safely.
Because we were not familiar with the results of using healthy
adult blood for CIK treatment and the patient had seemed to be
on the verge of death, we had asked the family to be mentally
prepared for the worst. Under normal circumstances, the survival
period would not be more than 3 months. After returning home to
Anyang the patient had her funeral arrangements made.
Relatives came to visit to bid farewell.  As our hospital did not
hold out any hope for her, in the ensuing 3 months we did not
follow up with her.

Unexpected good news emerged. On 19 September 2007
Professor Dr. Qi suddenly received a call from the patient saying
she had recovered and had left the hospital. He could not believe
his ears. On further questioning she revealed that in July upon
returning home she had checked into the local hospital. In July,
August September, the monthly CT scans had showed increasing
improvement in her condition. The metastatic foci in the lungs and
pleura had all disappeared. The metastases in the mediastinum
had decreased in size significantly.
6 October 2007 CT scans reveal absence of metastatic foci in the
chest, metastases in the mediastinum had completely
disappeared. The patient was mentally and physically very well.
2 November 2007 Came to Guangzhou for a PET/CT scan re-
examination:
Metastasis after surgery and chemotherapy. After subsequent
comprehensive treatment: (1) most of the tumours in the left
chest wall have disappeared, metabolism reduced significantly
indicating significant therapeutic effectiveness.  (2) the original
pervasive metastasis in both lungs have basically disappeared,
the original pleural effusion in both lung has been completely
absorbed. (3) The original multiple metastases in the lymph
nodes above the clavicles, underneath the left armpit, in both
porta pulmonis and mediastinum have largely disappeared. (4)
Multiple metastasis in T 10, 11, 12, 14 and right iliac bone.

The patient when we last contacted her is back at work.

Click here to link to Biotherapy information page.

More to come.....

We take pride in delivering world-class medical treatments to all
of our patients.
We are in the process of collecting data on all the past cases and
having them translated and collated so that you can share in our
proud achievements and in a new hope for a better future.

Back to the top
China's  Advanced  Therapies
Hospital for Cancer
Copyright © 2008
Capetown
Wonder Sdn Bhd.
All rights
reserved.